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H2O2 promotes heart regeneration through a derepression mechanism in ...
HRD1 promotes IGF-1R ubiquitination for degradation. A. The protein ...
The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator ...
Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell ...
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating ...
Autoubiquitination of the Hrd1 Ligase Triggers Protein ...
The S. cerevisiae Hrd1 ubiquitin ligase complex. Schematic ...
Models for substrate insertion into the Hrd1 complex and for activation ...
Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex ...
ER-associated degradation ligase HRD1 links ER stress to DNA damage ...
Hrd1 forms the retrotranslocation pore regulated by auto-ubiquitination ...
H2O2 Regulation of Vascular Function Through sGC mRNA Stabilization by ...
Human HRD1 Is an E3 Ubiquitin Ligase Involved in Degradation of ...
HRD1 knockdown inhibits cell migration and invasion in lung cancer ...
Schematic of the formation and the H2O2 directed quenching of ...
HRD1 ubiquitinates CPT2 by targeting K48 ubiquitination. (A ...
Proposed model for how Hrd1 influences CDV H protein to inhibit viral ...
Hrd1 inhibition of viral replication via its E3 ligase activity. A ...
HRD1 promotes the degradation of S100A8 through ubiquitination. (A) The ...
(a) Schematic representation of the HRD1 constructs. The panel ...
HRD1 and UBE2J1 target misfolded MHC class I heavy chains for ...
Rapoport and Liao labs determine the cryo-EM structure of the ERAD Hrd1 ...
Degradation of LBR1600* depends on the E3 ligases RNF5 and HRD1 ...
Hrd1 overcomes mutations disrupting helix α2:Ub interaction. (A and B ...
Reining in H2O2 for Safe Signaling: Cell
A–C. SH-SY5Y cells were treated with or without H2O2 (A) and rotenone ...
H2O2 treatment on primary hypothalamic neurons. (A) B1R expression ...
Correlation between HRD1 protein level and A β production in the brain ...
Endothelial H2O2 | Arteriosclerosis, Thrombosis, and Vascular Biology
Full article: HRD1 functions as a tumor suppressor in ovarian cancer by ...
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating ...
Dissection of Hrd1 complex stoichiometry by immunodepletion. A ...
Characterization of Hrd1 expression in cardiac myocytes. A, Diagram of ...
H2O2 activates Erk1/2 for myocardial regeneration. (A-B)... | Download ...
Hrd1 complex stoichiometry is altered upon Hrd1 overexpression. A ...
A positive genetic selection for transmembrane domain mutations in HRD1 ...
Kinetics of H2O2 accumulation and substrate conversion by HRP during ...
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis - Luo ...
Effect of human HRD1 on ubiquitination of HMGR. Naı¨veNaı¨ve 3T3 cells ...
HRD1 deficiency upregulated the expression of SIRT2 as determined using ...
Acute H2O2 signaling is in part mediated through TRPV1 activation. a ...
Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle ...
HRD1 is highly enriched in AVP neurons and upregulated during water ...
a) Configuration scheme of the H2O2 generation device in an ...
4-PBA inhibited ERAD gene HRD1. (A) WB results showing HRD1 protein ...
H2O2 signaling in mammalian cells. The binding of growth factors (e.g ...
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in ...
HRD1 is downregulated in apoptotic HKC-8 cells. a Glucose treatment ...
HRD1 knockdown promotes the proliferation of TNBC cells in vitro under ...
Exogenous H2S Induces Hrd1 S-sulfhydration and Prevents CD36 ...
Interaction and co-localization of Hrd1 with CDV H protein. A, B ...
H2O2 induced HLEC injury. HLEC SRA01/04 cells were treated with 400 μM ...
(A) Concentration of H2O2 on the induction of senescence in BV2 cells ...
a) Schematic depiction of ORR to H2O2 on a model Pd2Hg5 (001) surface ...
Structural basis of ER-associated protein degradation mediated by the ...
The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in ...
Endoplasmic reticulum-associated degradation and beyond: the ...
Rapoport Lab unveils the mechanism of ER-associated protein degradation ...
Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice ...
Membrane topology and N-linked glycosylation of human HRD1. A ...
Herp Regulates Hrd1-mediated Ubiquitylation in a Ubiquitin-like Domain ...
Deep mutational scanning highlights a role for cytosolic regions in ...
Characterization of protein complexes of the endoplasmic reticulum ...
Usa1 Functions as a Scaffold of the HRD-Ubiquitin Ligase: Molecular Cell
Frontiers | Unraveling the roles of endoplasmic reticulum-associated ...
Schematic representation of the H 2 O 2 reaction network in the ...
b,c. This behavior is due to the simultaneous presence of H 2 O 2 /HRP ...
Molecular mechanism for Hrd1-dependent retrotranslocation of misfolded ...
Retrotranslocation of a Misfolded Luminal ER Protein by the Ubiquitin ...
Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron ...
Probing substrate-Hrd1 interactions by disulfide crosslinking in live ...
HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein ...
The hypothetical mechanisms for the alleviation of H 2 O 2 -induced ...
Hrd1p and Hrd3p interacted via the Hrd1p NH2-terminal transmembrane ...
Interplay between physiological/pathophysiological H 2 O 2 generation ...
High mobility group box-1 release from H2O2-injured hepatocytes due to ...
Intracellular Sources of ROS/H2O2 in Health and Neurodegeneration ...
Exogenous H2S regulates the interaction between DGAT and Hrd1. A ...
HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic ...
A). Schematic illustration of mechanism of H 2 O 2-triggered release of ...
Regulation of Hrd1p by Hrd3p results in equal stoichiometry. (a) Hrd1p ...
(PDF) A Hrd way for MHC-II expression
A hypothetical scheme illustrating the inhibition of H 2 O 2 generation ...
11β-Hydroxysteroid Dehydrogenase-2 and Salt-Sensitive Hypertension ...
Scheme 1. HRP-catalyzed oxidations with H 2 O 2 and O 2 . S, substrate ...
Direct observation of autoubiquitination for an integral membrane ...
Involvement of heme oxygenase-1 (HO-1) in H2O2-induced apoptosis in ...